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Saúl Guerrero was the Leader of the Nuestra Sangre gang and was #2 on the FBI's most wanted list.

His case number Z181899Z was tattooed on Jane Doe's body. Bethany Mayfair was the officer in charge of his case. Tom Carter ordered that Guerrero had to be murdered inside federal prison before he could have a chance to talk to the authorities about Operation Daylight.

Years after his death, Guerrero appeared as one of Jane's ZIP-induced hallucinations in Times Square. Clad in his orange prison jumpsuit, he was taking a selfie with Sophia Varma and Ana Montes before noticing Jane and turning to the direction of Ivy Sands' final ZIP bomb.